A Monosodium Iodoacetate Osteoarthritis Lameness Model in Growing Pigs
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چکیده
منابع مشابه
Effects of salmon DNA fraction in vitro and in a monosodium iodoacetate-induced osteoarthritis rat model
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The etiology of osteoarthritis is multifactorial, with inflammatory, metabolic, and mechanical causes. Pain in osteoarthritis is initiated by mild intra-articular inflammation and degeneration of articular cartilage and subchondral bone. The principle of treatment with acetaminophen or non-steroidal anti-inflammatory drugs is to reduce pain and improve joint function. Recently, animal models fo...
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BACKGROUND The mechanisms driving osteoarthritic pain remain poorly understood, but there is increasing evidence for a role of the central nervous system in the chronification of pain. We used functional magnetic resonance imaging to investigate the influence of a model of unilateral knee osteoarthritis on nociceptive processing. RESULTS Four to five weeks post intra-articular injection of mo...
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PURPOSE: To evaluate the usefulness of a knee osteoarthritis model through functional, radiological and microscopic changes of the synovial membrane. METHODS: Forty eight rats were divided randomly into two groups. The first received 0.9% saline in the joint and corresponded to the control group. The second was submitted to experimental osteoarthritis of the right knee induced by monosodium i...
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ژورنال
عنوان ژورنال: Animals
سال: 2019
ISSN: 2076-2615
DOI: 10.3390/ani9070405